[ CAS No. 105743-53-1 ] {[proInfo.proName]}

Name: 105743-53-1|(S)-2-Amino-2,4-dimethylpentanoic acid|97%
Brand: Ambeed
SKU: A712606
Price: 67.0 USD
Availability: InStock
Rating: 93 (40 reviews)

,{[proInfo.pro_purity]}

Cat. No.: {[proInfo.prAm]}

2D 3D

Structure of 105743-53-1 * Storage: {[proInfo.prStorage]}

Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

For Research Only 110K+ Compounds Competitive Price 1-2 Day Shipping

Quality Control of [ 105743-53-1 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 105743-53-1 ]

SDS Specification

Alternatived Products of [ 105743-53-1 ]

Product Details of [ 105743-53-1 ]

CAS No. :	105743-53-1	MDL No. :	MFCD01716279
Formula :	C₇H₁₅NO₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	ARSWQPLPYROOBG-ZETCQYMHSA-N
M.W :	145.20	Pubchem ID :	446181
Synonyms :

Calculated chemistry of [ 105743-53-1 ]

Physicochemical Properties

Num. heavy atoms :	10
Num. arom. heavy atoms :	0
Fraction Csp3 :	0.86
Num. rotatable bonds :	3
Num. H-bond acceptors :	3.0
Num. H-bond donors :	2.0
Molar Refractivity :	40.28
TPSA :	63.32 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	No
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-8.24 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.53
Log Po/w (XLOGP3) :	-1.49
Log Po/w (WLOGP) :	0.83
Log Po/w (MLOGP) :	-1.47
Log Po/w (SILICOS-IT) :	0.1
Consensus Log Po/w :	-0.1

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	0.4
Solubility :	362.0 mg/ml ; 2.49 mol/l
Class :	Highly soluble
Log S (Ali) :	0.67
Solubility :	672.0 mg/ml ; 4.63 mol/l
Class :	Highly soluble
Log S (SILICOS-IT) :	-0.54
Solubility :	42.3 mg/ml ; 0.291 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.48

Safety of [ 105743-53-1 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 105743-53-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 105743-53-1 ]
Downstream synthetic route of [ 105743-53-1 ]

[ 105743-53-1 ] Synthesis Path-Upstream 1~1

1
[ 129786-65-8 ]
[ 29589-03-5 ]
[ 105743-53-1 ]

Reference： [1] Journal of Organic Chemistry, 1990, vol. 55, # 20, p. 5437 - 5439

[ 105743-53-1 ] Synthesis Path-Downstream 1~14

1
[ 129786-65-8 ]
[ 29589-03-5 ]
[ 105743-53-1 ]

Reference： [1]Journal of Organic Chemistry,1990,vol. 55,p. 5437 - 5439

2
[ 113509-60-7 ]
[ 105743-53-1 ]
[ 113565-54-1 ]

Reference： [1]Journal of Organic Chemistry,1988,vol. 53,p. 1826 - 1827

3
(1R,2S,5R)-8-Phenylmenthyl N-benzoyl-α-methylleucinate [ No CAS ]
[ 29589-03-5 ]
[ 105743-53-1 ]

Reference： [1]Journal of Organic Chemistry,1995,vol. 60,p. 1233 - 1238

4
(3S,6R)-3-Isobutyl-6-isopropyl-3-methyl-5-phenyl-3,6-dihydro-2H-1,4-oxazin-2-one [ No CAS ]
[ 105743-53-1 ]

Reference： [1]Synthesis,1999,p. 704 - 717
[2]Tetrahedron Asymmetry,1998,vol. 9,p. 2769 - 2772

5
[ 24424-99-5 ]
[ 105743-53-1 ]
C₁₂H₂₅NO₃ [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry,2009,vol. 17,p. 4486 - 4495

6
[ 1266681-15-5 ]
[ 105743-53-1 ]

Reference： [1]Journal of Organic Chemistry,2011,vol. 76,p. 1621 - 1633

7
[ 105743-53-1 ]
[ 2493-02-9 ]
[ 1431755-12-2 ]

Yield	Reaction Conditions	Operation in experiment
	With triethylamine; In dichloromethane;	2-([(4-Bromophenyl)amino]carbonyl}amino)-2,4-dimethylpentanoic acid Compound 24 was prepared according to Scheme 3. <strong>[105743-53-1]2-methyl-leucine</strong> (CAS 144-24-1) was reacted with a 4-bromophenylisocyanate (CAS 2493-0-9). 1H NMR (CD3OD, 300 MHz) delta: 7.31-7.39 (m, 2H), 7.22-7.30 (m, 2H), 1.80-1.92 (m, 2H), 1.71-1.82 (m, 1H), 1.56-1.67 (m, 2H), 1.44 (s, 3H), 0.98 (d, J=1.2 Hz, 3H), 0.95 (d, J=1.2 Hz, 3H).

Reference： [1]Patent: US2013/123496,2013,A1 .Location in patent: Paragraph 0181; 0207; 0208; 0209

8
C₁₄H₁₉N₃O₂ [ No CAS ]
[ 29589-03-5 ]
[ 105743-53-1 ]

Yield	Reaction Conditions	Operation in experiment
	With palladium 10% on activated carbon; hydrogen; In methanol; at 20℃; for 3h;Inert atmosphere;	To a solution of the azide (0.10 mmol) in THF (2.0 ml) were added 10%Pd/C (10 mol%). After stirring for 0.5-24 h at room temperature under H2atmosphere, the mixture was filtered with a pad of Celite.Concentration of the solvent in vacuo followed by purification of the residueon silica gel column (AcOEt:n-Hexane1:1) gave the desired amine.

Reference： [1]Tetrahedron Letters,2015,vol. 56,p. 3169 - 3171

9
[ 80870-32-2 ]
[ 74-88-4 ]
[ 105743-53-1 ]

Yield	Reaction Conditions	Operation in experiment
		N-benzylidenebis surcrose tert-butyl (13.8 mg, 50mumol) (5) in a toluene solution (2.5 ml) (S)-Maruoka catalyst (registered trademark; nagase Co. ; (CAS: 851942-89-7) (18.7 mg, 25mumol) is added, 0 C cooled by ice bath. An argon atmosphere, adding aq. unsatd. cesium hydroxide (3.75g), 30 minutes at 0 C is violently agitated. The methyl iodide of 50 mm prepared by adding a toluene solution (40muL, 2mumol), argon atmosphere, a vigorous stirring at 0 C (methyl iodide is added and a reaction start point). In HPLC perfluoroalkylated for confirming the progress of the reaction, the reaction from 5 minutes after the start, after 10 minutes, after 15 minutes, 20 minutes after the sampling is performed and, by calculating a conversion rate of methyl iodide HPLC analysis. The result of monitoring is confirmed by HPLC before the reaction, the reaction mixture from the starting reaction (5 ml) 25 minutes after pouring water, organic layer separates politeness. The optical part (100muL) extracted org. sampled for checking the purity, the remaining organic layer is heated to 60 C 4N hydrochloric acid (2.5 ml, 10mmol) in addition to, a vigorous stirring at 60 C (after 30 minutes from the start of reaction). With the progress of the hydrolysis reaction for HPLC, in addition to the organic layer is from 5 minutes after 4N hydrochloric acid solution, after 10 minutes, after 15 minutes, 20 minutes after the sampling is performed and, by HPLC analysis, alpha reaction intermediate and tert-butyl-methylleucine alpha-purpose of conversion rate is calculated from the ratio of methylleucine. In addition to the organic layer 25 minutes after 4N hydrochloric acid solution from the agitation is stopped, by separating the water layer, and a purpose compd. (6) ((S)-alpha-methylleucine) obtained as an aqueous solution of a reaction mixture (60 minutes after the start of reaction). In this embodiment, alpha-methylleucine obtd. conversioin yield from the 56% of methyl iodide.In this embodiment, the optical obtd. compd. for measuring purity, sampled hydroxycitric aq. 1M (0.5 ml) is added to the organic layer, 30 minutes after stirring, tert-butyl ether (0.5 ml) in a washer 3 times. The separated water layer and sodium carbonate (100 mg), ethyl acetate (0.5 ml), triethylamineborane (30muL), chlorobenzoyl chlorides 4 - (10muL) is added, 30 min. The organic layer separating, concentrating, hexane/2-propanol concentrated residue is added to the mixed solution of (80/20) (1 ml), and the sample solution, analyzed by HPLC a [Daicel Chiralpak AD-H; eluent: Phenylbicyclohexane/2-propanol = 985/15, velocity 0.5 ml/min; holding time : (R) body = 19.5 min, the body (S) = 24.4 min]. In this embodiment, the purity of the obtained optical 93% ee. Furthermore, in this embodiment, the conversion rate cycloalkylation obtd. in Table 5, the hydrolysis reaction of the conversion rate is shown in Table 6.

Reference： [1]Patent: JP2016/74605,2016,A .Location in patent: Paragraph 0130-0133

10
[ 82911-69-1 ]
[ 105743-53-1 ]
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,4-dimethylpentanoic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
60%	With sodium hydroxide; In water; acetone; at 30℃; for 12h;pH 9.5;Large scale;	Add compound 3 (0.371 kg, 2.56 mol) to a three-necked flask. Acetone (2 L), water (2 L), Then add sodium hydroxide (0.123 kg, 3.07 mol) and Fmoc-OSu (0.862 kg, 2.56 mol). The reaction mixture was adjusted to pH 9.5 with 4N sodium hydroxide and stirred at 30 C for 12 hours. Extraction with petroleum ether (300 mL x 3); aqueous phase acidified to pH 2 with 1 N hydrochloric acid, ethyl acetate (300 mL x 3); Wash with saturated brine (500 mL), dry over sodium sulfate and filtered. The filtrate was spun dry to give a white solid. Target compound 5 (0.563 kg, 1.53 mol, 60%, Pu: 98%, ee: 99%).

Reference： [1]Patent: CN109369460,2019,A .Location in patent: Paragraph 0010; 0011; 0012

11
[ 865468-88-8 ]
[ 105743-53-1 ]

Reference： [1]Patent: CN109369460,2019,A

12
C₁₅H₁₉NO₄ [ No CAS ]
[ 105743-53-1 ]

Yield	Reaction Conditions	Operation in experiment
100%	With palladium 10% on activated carbon; hydrogen; In methanol; at 30℃; for 6h;Large scale;	Add compound 2 (0.709 kg, 2.56 mol) and methanol (5 L) to a three-necked flask and then add the target charcoal (10%, 70 g). Hydrogen was introduced and stirred at 30 C for 6 hours. Filtration, the filtrate was spun dry to give a white solid. Compound 3 (0.371 kg, 2.56 mol, 100%). Used directly in the next reaction;

Reference： [1]Patent: CN109369460,2019,A .Location in patent: Paragraph 0010; 0011; 0012

13
[ 85-44-9 ]
[ 105743-53-1 ]
C₁₅H₁₄⁽²⁾H₃NO₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: toluene / 16 h / 100 °C / Schlenk technique 2: N-(2-(dimethylamino)ethyl)-2,4,6-triisopropylbenzamide; 1,1,1,3,3,3-hexafluoropropan-2-ol-d1; palladium diacetate; silver carbonate / 24 h / 90 °C / Schlenk technique

Reference： [1]Mal, Sourjya; Uttry, Alexander; Van Gemmeren, Manuel [Journal of the American Chemical Society, 2021, vol. 143, # 29, p. 10895 - 10901]

14
[ 85-44-9 ]
[ 105743-53-1 ]
(S)-2-(1,3-dioxoisoindolin-2-yl)-2,4-dimethylpentanoic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
39%	In toluene at 100℃; for 16h; Schlenk technique;

Reference： [1]Mal, Sourjya; Uttry, Alexander; Van Gemmeren, Manuel [Journal of the American Chemical Society, 2021, vol. 143, # 29, p. 10895 - 10901]

Same Skeleton Products

Related Products

Historical Records

Related Functional Groups of
[ 105743-53-1 ]

Amino Acid Derivatives

[ 105815-96-1 ]

(S)-2-Amino-2-methylhexanoic acid

Similarity: 1.00

[ 105815-95-0 ]

(R)-2-Amino-2-methylhexanoic acid

Similarity: 1.00

[ 6949-77-5 ]

1-Aminocycloheptanecarboxylic acid

Similarity: 1.00

[ 170984-72-2 ]

(S)-2-Amino-2-ethylpentanedioic acid

Similarity: 1.00

[ 71-90-9 ]

2-Amino-2-methylpentanedioic acid

Similarity: 1.00

Ghs Precautionary Statements

Precautionary Statements-General
Code	Phrase
P101	If medical advice is needed,have product container or label at hand.
P102	Keep out of reach of children.
P103	Read label before use
Prevention
Code	Phrase
P201	Obtain special instructions before use.
P202	Do not handle until all safety precautions have been read and understood.
P210	Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211	Do not spray on an open flame or other ignition source.
P220	Keep/Store away from clothing/combustible materials.
P221	Take any precaution to avoid mixing with combustibles
P222	Do not allow contact with air.
P223	Keep away from any possible contact with water, because of violent reaction and possible flash fire.
P230	Keep wetted
P231	Handle under inert gas.
P232	Protect from moisture.
P233	Keep container tightly closed.
P234	Keep only in original container.
P235	Keep cool
P240	Ground/bond container and receiving equipment.
P241	Use explosion-proof electrical/ventilating/lighting/equipment.
P242	Use only non-sparking tools.
P243	Take precautionary measures against static discharge.
P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]}	{[ getRatePrice(item.pr_usd, 1,1) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]}	{[ item.pr_usastock ]}	Inquiry -	{[ item.pr_chinastock ]}	Inquiry -

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 105743-53-1 ] {[proInfo.proName]}

Quality Control of [ 105743-53-1 ]

Related Doc. of [ 105743-53-1 ]

Product Details of [ 105743-53-1 ]

Calculated chemistry of [ 105743-53-1 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 105743-53-1 ]

Application In Synthesis of [ 105743-53-1 ]

[ 105743-53-1 ] Synthesis Path-Upstream 1~1

[ 105743-53-1 ] Synthesis Path-Downstream 1~14

Related Functional Groups of [ 105743-53-1 ]

Amino Acid Derivatives

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 105743-53-1 ]