100841-20-1Relevant articles and documents
The reaction of β-amino alcohols with 1,1′ -carbonyldiimidazole - Influence of the nitrogen substituent on the reaction course
Cutugno, Sara,Martelli, Gianluca,Negro, Lucia,Savoia, Diego
, p. 517 - 522 (2001)
The reaction of β-amino alcohols with 1,1′carbonyldiimidazole in dichloromethane is affected by the size of the nitrogen substituent. 1,3-Oxazolidin-2-ones are exclusively obtained from N-H, N-methyl and N-arylmethyl derivatives. O-(1-Imidazolyl)carbonyl derivatives are formed as intermediates from N-[1-(2-pyridyl)alkyl]-(S)-valinol and are mainly or exclusively converted into aziridines in the presence of water, although the cyclization is impeded by large N-substituents such as triphenylmethyl.
Preparation of Tritylamino Alcohols
Barlos, Kleomenis,Papaioannou, Dionysios,Patrianakou, Stella,Tsegenidis, Theodoros
, p. 952 - 956 (2007/10/02)
N-Tritylamino acid trimethylsilyl esters 2 were mildly reduced with LiAlH4 to give N-tritylamino alcohols 3 in high yields and purity.Other methods provided 3 in lower yields.
