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Antibody detects endogenous levels of total GPR110.
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.
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Protein Aliases: Adhesion G-protein coupled receptor F1; G protein-coupled receptor 110; G protein-coupled receptor KPG_012; G protein-coupled receptor PGR19; G-protein coupled receptor 110; G-protein coupled receptor KPG_012; internal gene name of KIRIN laboratory:M5; probable G-protein coupled receptor 110; seven transmembrane helix receptor
Gene Aliases: 5031409J19Rik; ADGRF1; GPR110; hGPCR36; KPG_009; KPG_012; PGR19
UniProt ID: (Human) Q5T601, (Mouse) Q8VEC3
Entrez Gene ID: (Human) 266977, (Mouse) 77596
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