Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Antibody detects endogenous levels of total NUS1.
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cis-prenyltransferase subunit NgBR; dehydrodolichyl diphosphate syntase complex subunit NUS1; Dehydrodolichyl diphosphate synthase complex subunit NUS1; di-trans,poly-cis-decaprenylcistransferase; NgBR; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog; transport and golgi organization 14 homolog
Gene Aliases: 1600027K07Rik; AU019165; AW538011; BC003223; C6orf68; D10Ertd438e; MGC:7199; NGBR; NUS1; RGD1307879; TANGO14
UniProt ID: (Human) Q96E22, (Mouse) Q99LJ8
Entrez Gene ID: (Human) 116150, (Rat) 294400, (Mouse) 52014
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